Uroplakin 3A
Product Specifications
Gene Name
[UPK3A]
NCBI Gene ID
7380
Reactivity
Human.
Storage Conditions
Store at 2 to 8 °C. Antibody is stable for 24 months.
Specificity
Uroplakin-3A (UPK3A) is a component of the asymmetric unit membrane (AUM). It is a highly specialized bio-membrane made by terminally differentiated urothelial cells. The protein may play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. UPK3A also contributes to the formation of urothelial glycocalyx, which may play an important role in preventing bacterial adherence through FimH bacterial protein binding leading to bladder infection. UPK3A has been shown as a helpful marker for the detection of bladder cancer.
Other Gene Names
[UPK3A; UPK3A; UP3A; UPK3; UPIII; UPIIIA; UPK3; UP3a; UPIII]
Short Name
[Uroplakin 3A]
Other Product Names
[uroplakin-3a isoform 2; Uroplakin-3a; uroplakin-3a; uroplakin 3; uroplakin III; uroplakin 3A; Uroplakin III; UPIII]
NCBI GI Number
266456217
NCBI Accession Number
NP_001161046.1
NCBI GB Accession Number
NM_001167574.1
Uniprot Accession Number
O75631
Available Sizes
Curated Selection
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