Histone H3 Antibody
Product Specifications
Background
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4) . The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.
NCBI Gene ID
8290
Swiss Prot
Q16695
Host
Rabbit
Reactivity
Human, Mouse, Rat, Other
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 50 to the C-terminus of human HIST3H3 (NP_003484.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
Affinity purification
Positive Control
Jurkat
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=18-617
Calculated Molecular Weight
Observed: 17kDa
Fragment
IgG
Symbol
HIST3H3
Positive Control 2
A-431
Positive Control 3
HeLa
Positive Control 4
Mouse liver
Positive Control 5
Mouse testis
Positive Control 6
Rat kidney
NCBI Official Name
Histone cluster 3, H3
NCBI Organism
Homo sapiens
Other Product Names
H3F3A, H3t, H3.4, H3/g, H3FT
Tested Applications
WB, IHC, IP
Physical Properties
Liquid
Curated Selection
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