CEP76 polyclonal antibody
Product Specifications
Background
Centrosomes are the major microtubule-organizing centers of mammalian cells. They are composed of a centriole pair and surrounding microtubule-nucleating material termed pericentriolar material (PCM) . Bipolar mitotic spindle assembly relies on two intertwined processes: centriole duplication and centrosome maturation. Failure to properly orchestrate centrosome duplication and maturation is subsequently linked to spindle defects, which can result in aneuploidy and promote cancer progression. The CEP76 (centrosomal protein of 76 kDa) gene encodes a protein of 659 amino acids. The CEP76 protein is homologous among several species including human, mouse, rat and xenopus, suggesting a conserved function.
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Centrosomal protein of 76 kDa; Cep76; CEP76; centrosomal protein 76; C18orf9
Swiss Prot
Q8TAP6
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to Human CEP76.
Conjugation
Unconjugated
Applications
WB IHC
Dilution
WB:1:500~1:1000 IHC:1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 76 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
CEP76 polyclonal antibody detects endogenous levels of CEP76 protein.
Applications Notes
Western blot (WB) analysis of CEP76 polyclonal antibody at 1:500 dilution LaneA:COS-7 whole cell lysate LaneB:PC3 whole cell lysate LaneC:CT26 whole cell lysate LaneD:PC12 whole cell lysate
Host or Source
Rabbit
CAS Number
9007-83-4
Available Sizes
Curated Selection
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