Uhrf2 Antibody

Product Specifications

Background

This gene encodes a nuclear protein which is involved in cell-cycle regulation. The encoded protein is a ubiquitin-ligase capable of ubiquinating PCNP (PEST-containing nuclear protein), and together they may play a role in tumorigenesis. The encoded protein contains an NIRF_N domain, a PHD finger, a set- and ring-associated (SRA) domain, and a RING finger domain and several of these domains have been shown to be essential for the regulation of cell proliferation. This protein may also have a role in intranuclear degradation of polyglutamine aggregates. Alternative splicing results in multiple transcript variants some of which are non-protein coding.

NCBI Gene ID

109113

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 76-359 of mouse Uhrf2 (NP_659122.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Apoptosis, Cell Cycle

Purification

Affinity purification

Positive Control

Jurkat

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 110kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

UHRF2

Positive Control 2

U-87MG

Positive Control 3

HeLa

Positive Control 4

Mouse liver

Positive Control 5

Rat thymus

NCBI Official Name

Ubiquitin-like, containing PHD and RING finger domains 2

NCBI Organism

Mus musculus

Other Product Names

2310065A22Rik, AI42627AW214556, D130071B19Rik, Nirf, E3 ubiquitin-protein ligase UHRF2, Np95-like ring finger protein, RING-type E3 ubiquitin transferase UHRF2, nuclear protein 97, nuclear zinc finger protein Np97, ubiquitin-like PHD and RING finger domain-containing protein 2, ubiquitin-like-containing PHD and RING finger domains protein 2