Uhrf2 Antibody
Product Specifications
Background
This gene encodes a nuclear protein which is involved in cell-cycle regulation. The encoded protein is a ubiquitin-ligase capable of ubiquinating PCNP (PEST-containing nuclear protein), and together they may play a role in tumorigenesis. The encoded protein contains an NIRF_N domain, a PHD finger, a set- and ring-associated (SRA) domain, and a RING finger domain and several of these domains have been shown to be essential for the regulation of cell proliferation. This protein may also have a role in intranuclear degradation of polyglutamine aggregates. Alternative splicing results in multiple transcript variants some of which are non-protein coding.
NCBI Gene ID
109113
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 76-359 of mouse Uhrf2 (NP_659122.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Cell Cycle
Purification
Affinity purification
Positive Control
Jurkat
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=18-614
Calculated Molecular Weight
Observed: 110kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
UHRF2
Positive Control 2
U-87MG
Positive Control 3
HeLa
Positive Control 4
Mouse liver
Positive Control 5
Rat thymus
NCBI Official Name
Ubiquitin-like, containing PHD and RING finger domains 2
NCBI Organism
Mus musculus
Other Product Names
2310065A22Rik, AI42627AW214556, D130071B19Rik, Nirf, E3 ubiquitin-protein ligase UHRF2, Np95-like ring finger protein, RING-type E3 ubiquitin transferase UHRF2, nuclear protein 97, nuclear zinc finger protein Np97, ubiquitin-like PHD and RING finger domain-containing protein 2, ubiquitin-like-containing PHD and RING finger domains protein 2
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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