HLA-DQA2 Antibody
Product Specifications
Background
This gene belongs to the HLA class II alpha chain family. The encoded protein forms a heterodimer with a class II beta chain. It is located in intracellular vesicles and plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (B lymphocytes, dendritic cells, macrophages) and are used to present antigenic peptides on the cell surface to be recognized by CD4 T-cells. [provided by RefSeq].
NCBI Gene ID
3118
Swiss Prot
P01906
Accession Number
P01906
Host
Rabbit
Reactivity
Human
Immunogen
This HLA-DQA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-66 amino acids from the Central region of human HLA-DQA2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=60-924
Calculated Molecular Weight
28 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
HLA-DQA2
NCBI Official Name
HLA class II histocompatibility antigen, DQ alpha 2 chain
NCBI Organism
Homo sapiens
Background Reference 01
Ucisik-Akkaya, E., et al. Mol. Hum. Reprod. 16 (10) :770-777 (2010)
Background Reference 02
Hor, H., et al. Nat. Genet. 42 (9) :786-789 (2010)
Background Reference 03
Petukhova, L., et al. Nature 466 (7302) :113-117 (2010)
Background Reference 04
Davila, S., et al. Genes Immun. 11 (3) :232-238 (2010)
Other Product Names
HLA class II histocompatibility antigen, DQ alpha 2 chain, DX alpha chain, HLA class II histocompatibility antigen, DQ (6) alpha chain, HLA-DQA1, MHC class II DQA2, HLA-DQA2, HLA-DXA
Tested Applications
WB
Protein ID
122192
Physical Properties
Liquid
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