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HLA-DQA2 Antibody

Product Specifications

Background

This gene belongs to the HLA class II alpha chain family. The encoded protein forms a heterodimer with a class II beta chain. It is located in intracellular vesicles and plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (B lymphocytes, dendritic cells, macrophages) and are used to present antigenic peptides on the cell surface to be recognized by CD4 T-cells. [provided by RefSeq].

NCBI Gene ID

3118

Swiss Prot

P01906

Accession Number

P01906

Host

Rabbit

Reactivity

Human

Immunogen

This HLA-DQA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-66 amino acids from the Central region of human HLA-DQA2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

28 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

HLA-DQA2

NCBI Official Name

HLA class II histocompatibility antigen, DQ alpha 2 chain

NCBI Organism

Homo sapiens

Background Reference 01

Ucisik-Akkaya, E., et al. Mol. Hum. Reprod. 16 (10) :770-777 (2010)

Background Reference 02

Hor, H., et al. Nat. Genet. 42 (9) :786-789 (2010)

Background Reference 03

Petukhova, L., et al. Nature 466 (7302) :113-117 (2010)

Background Reference 04

Davila, S., et al. Genes Immun. 11 (3) :232-238 (2010)

Other Product Names

HLA class II histocompatibility antigen, DQ alpha 2 chain, DX alpha chain, HLA class II histocompatibility antigen, DQ (6) alpha chain, HLA-DQA1, MHC class II DQA2, HLA-DQA2, HLA-DXA

Tested Applications

WB

Protein ID

122192

Physical Properties

Liquid

Frequently Asked Questions

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