HuR / ELAVL1 Antibody, KO Validated
Product Specifications
Background
The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy.
NCBI Gene ID
1994
Swiss Prot
Q15717
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-326 of human HuR / ELAVL1 (NP_001410.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Validation
Antibody is Knockout validated.
Field of Research
Other
Purification
Affinity purification
Positive Control
U-251MG
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=16-418
Calculated Molecular Weight
Observed: 37kDa
Fragment
IgG
Symbol
ELAVL1
Positive Control 2
HeLa
Positive Control 3
Jurkat
Positive Control 4
K-562
Positive Control 5
PC-3
NCBI Official Name
ELAV like RNA binding protein 1
NCBI Organism
Homo sapiens
Other Product Names
ELAVL1, ELAV1, Hua, HUR, Hu antigen R, ELAV-like protein 1, Hu-antigen R, MelG
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
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