MYOF Antibody
Product Specifications
Background
Mutations in dysferlin, a protein associated with the plasma membrane, can cause muscle weakness that affects both proximal and distal muscles. The protein encoded by this gene is a type II membrane protein that is structurally similar to dysferlin. It is a member of the ferlin family and associates with both plasma and nuclear membranes. The protein contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. Two transcript variants encoding different isoforms have been found for this gene. Other possible variants have been detected, but their full-length nature has not been determined.
NCBI Gene ID
26509
Swiss Prot
Q9NZM1
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human MYOF (NP_038479.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
Affinity purification
Positive Control
U-251MG
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 250kDa
Fragment
IgG
Applications Notes
WB: 1:200 - 1:2000
Symbol
MYOF
Positive Control 2
A-549
Positive Control 3
HeLa
Positive Control 4
NIH/3T3
NCBI Official Name
Myoferlin
NCBI Organism
Homo sapiens
Other Product Names
FER1L3, myoferlin, fer-1-like 3, myoferlin, fer-1-like family member 3, fer-1-like protein 3
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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