Mc-MMAD

Product Specifications

CAS Number

1401963-15-2

Target

Microtubule Associated|||ADC Cytotoxin|||Drug-Linker Conjugates for ADC

Related Pathways

Antibody-drug Conjugate/ADC Related|||Cytoskeletal Signaling

Purity

0.9804

Bioactivity

Mc-MMAD is monomethyl auristatin D (MMAD) modified with the protective group maleimidocaproyl (Mc) . MMAD is a potent tubulin microtubule inhibitor that suppresses cancer cell proliferation and is commonly employed as a toxic payload in ADC synthesis.

Smiles

[H][C@]([C@@H](C)CC)([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)c1nccs1)OC)N(C)C(=O)[C@@H](NC(=O)[C@H](C(C)C)N(C)C(=O)CCCCCN1C(=O)C=CC1=O)C(C)C