CYTH4 Antibody
Product Specifications
Background
This gene encodes a member of the PSCD family of proteins, which have an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family function as GEPs for ADP-ribosylation factors (ARFs), which are guanine nucleotide-binding proteins involved in vesicular trafficking pathways. This protein exhibits GEP activity in vitro with ARF1 and ARF5, but is inactive with ARF6. Alternatively spliced transcript variants have been found for this gene.
NCBI Gene ID
27128
Swiss Prot
Q9UIA0
Host
Rabbit
Reactivity
Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human CYTH4 (NP_037517.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
Affinity purification
Positive Control
Mouse liver
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 46kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
CYTH4
Positive Control 2
Mouse brain
Positive Control 3
Rat brain
NCBI Official Name
Cytohesin 4
NCBI Organism
Homo sapiens
Other Product Names
PSCD4, CYT4, DJ63G5.1, CYTOHESIN-4, pleckstrin homology, Sec7 and coiled/coil domains 4, cytohesin-4, PSCD4
Tested Applications
WB
Physical Properties
Liquid
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