FT-1518

FT-1518 is a new generation selective, potent and oral bioavailable mTORC1 and mTORC2 inhibitor, and exhibits antitumor activity.

Product Specifications

CAS Number

[1313026-58-2]

UNSPSC

12352005

Target

MTOR

Type

Reference compound

Related Pathways

PI3K/Akt/mTOR

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/FT-1518.html

Purity

98.62

Solubility

DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

CCC(N1C2=NC(N3CC4OC(CC4)C3)=NC(C5=NC=C(N)N=C5)=C2N=C1)CC

Molecular Formula

C20H26N8O

Molecular Weight

394.47

References & Citations

[1]Alain C. Mita, et al. Abstract 137: FT-1518, a new generation selective and potent mTORC1 and mTORC2 inhibitor: an in vitro and in vivo profile. Cancer Res 2017;77 (13 Suppl) .

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

MTORC1; mTORC2

Available Sizes

Curated Selection

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