ERLIN1 Antibody
Product Specifications
Background
The protein encoded by this gene is part of a protein complex that mediates degradation of inositol 1,4,5-trisphosphate receptors in the endoplasmic reticulum. The encoded protein also binds cholesterol and regulates the SREBP signaling pathway, which promotes cellular cholesterol homeostasis. Defects in this gene have been associated with spastic paraplegia 62.
NCBI Gene ID
10613
Swiss Prot
O75477
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 259-348 of human ERLIN1 (NP_006450.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Affinity purification
Positive Control
293T
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 39kDa
Fragment
IgG
Symbol
ERLIN1
Positive Control 2
HepG2
Positive Control 3
BxPC-3
Positive Control 4
DU145
Positive Control 5
OVCAR3
Positive Control 6
Mouse kidney
NCBI Official Name
ER lipid raft associated 1
NCBI Organism
Homo sapiens
Other Product Names
ERLIN1, C10orf69, Erlin-1, KE04, KEO4, RP11-316M21.1, SPFH1, SPG62
Tested Applications
WB, IHC
Physical Properties
Liquid
Curated Selection
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