RNF6 Antibody
Product Specifications
Background
The protein encoded by this gene contains a RING-H2 finger motif. Deletions and mutations in this gene were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse counterpart suggested a role of this protein in the transcription regulation that controls germinal differentiation. Multiple alternatively spliced transcript variants encoding the same protein are observed.
NCBI Gene ID
6049
Swiss Prot
Q9Y252
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human RNF6 (NP_898864.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
Affinity purification
Positive Control
DU145
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 78kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
RNF6
Positive Control 2
U-87MG
Positive Control 3
Mouse testis
Positive Control 4
Rat testis
NCBI Official Name
Ring finger protein (C3H2C3 type) 6
NCBI Organism
Homo sapiens
Other Product Names
RNF6, DKFZp686P0776, SPG2
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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