PRKAG2 Antibody
Product Specifications
Background
AMP-activated protein kinase (AMPK) is a heterotrimeric protein composed of a catalytic alpha subunit, a noncatalytic beta subunit, and a noncatalytic regulatory gamma subunit. Various forms of each of these subunits exist, encoded by different genes. AMPK is an important energy-sensing enzyme that monitors cellular energy status and functions by inactivating key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This gene is a member of the AMPK gamma subunit family. Mutations in this gene have been associated with Wolff-Parkinson-White syndrome, familial hypertrophic cardiomyopathy, and glycogen storage disease of the heart. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
NCBI Gene ID
51422
Swiss Prot
Q9UGJ0
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-328 of human PRKAG2 (NP_077747.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Autophagy, Cell Cycle, Signal Transduction
Purification
Affinity purification
Positive Control
Mouse brain
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 63kDa
Fragment
IgG
Symbol
PRKAG2
Positive Control 2
Mouse heart
Positive Control 3
Rat skeletal muscle
Positive Control 4
Rat liver
NCBI Official Name
Protein kinase AMP-activated non-catalytic subunit gamma 2
NCBI Organism
Homo sapiens
Other Product Names
AAKG, AAKG2, CMH6, H91620p, WPWS, 5'-AMP-activated protein kinase subunit gamma-2, AMPK subunit gamma-2, epididymis secretory sperm binding protein, protein kinase, AMP-activated, gamma 2 non-catalytic subunit
Tested Applications
WB, IHC
Physical Properties
Liquid
Curated Selection
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