VPA (Valproic acid)

Product Specifications

CAS Number

99-66-1

Synonyms

2-Propylvaleric Acid, Valproate

SKU

C09767-25mg

Target

HDAC

Applications

DNA Damage/DNA Repair

Smiles

CCCC (CCC) C (=O) O

Molecular Formula

C8H16O2

Additionnal Information

VPA (Valproic acid) is a fatty acid with anticonvulsant properties used in the treatment of epilepsy. It is also a histone deacetylase (HDAC) inhibitor and is under investigation for treatment of HIV and various cancers. Valproic acid (VPA) induces autophagy and mitophagy by upregulation of BNIP3 and mitochondrial biogenesis by upregulating PGC-1α. Valproic acid activates Notch-1 signaling.