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PDE7B Antibody

Product Specifications

Background

The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a cAMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family.

NCBI Gene ID

27115

Swiss Prot

Q9NP56

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 341-450 of human PDE7B (NP_061818.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Signal Transduction

Purification

Affinity purification

Positive Control

Mouse brain

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 52kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

PDE7B

Positive Control 2

Mouse kidney

Positive Control 3

Rat brain

NCBI Official Name

Phosphodiesterase 7B

NCBI Organism

Homo sapiens

Other Product Names

PDE7B, BA472E5.1, Phosphodiesterase 7B

Tested Applications

WB

Physical Properties

Liquid

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