TMEFF2 Antibody

Product Specifications

Background

This gene encodes a member of the tomoregulin family of transmembrane proteins. This protein has been shown to function as both an oncogene and a tumor suppressor depending on the cellular context and may regulate prostate cancer cell invasion. Multiple soluble forms of this protein have been identified that arise from both an alternative splice variant and ectodomain shedding. Additionally, this gene has been found to be hypermethylated in multiple cancer types. Alternative splicing results in multiple transcript variants.

NCBI Gene ID

23671

Swiss Prot

Q9UIK5

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 41-320 of human TMEFF2 (NP_057276.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Growth Factors

Purification

Affinity purification

Positive Control

U-87MG

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 41kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

TMEFF2

Positive Control 2

A-549

Positive Control 3

SW480

Positive Control 4

HeLa

Positive Control 5

Mouse brain

Positive Control 6

Mouse lung

NCBI Official Name

Transmembrane protein with EGF like and two follistatin like domains 2

NCBI Organism

Homo sapiens

Other Product Names

CT120.2, HPP1, TENB2, TPEF, TR, TR-2, tomoregulin-2, cancer/testis antigen family 12member 2, hyperplastic polyposis protein 1, transmembrane protein TENB2, transmembrane protein with EGF-like and two follistatin-like domains