Microtubule inhibitor 5
Product Specifications
CAS Number
2416338-55-9
Target
Microtubule Associated|||Others
Related Pathways
Others|||Cytoskeletal Signaling
Bioactivity
Microtubule inhibitor 5 (compound 17f) is a highly potent cytotoxic agent that inhibits microtubule function, exhibiting a substantial cytotoxic effect on NCI-H460 cells with an IC50 value of 154.5 nM. Additionally, this compound demonstrates excellent cell permeability [1].
Smiles
C(=C\1/C(=O)N/C(=C\C2=CC=CO2)/C(=O)N1)\C3=CC(OC4=CC=C(F)C=C4)=CC=C3
Molecular Formula
C22H15FN2O4
Molecular Weight
390.36
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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