DAG1 Antibody
Product Specifications
Background
This gene encodes dystroglycan, a central component of dystrophin-glycoprotein complex that links the extracellular matrix and the cytoskeleton in the skeletal muscle. The encoded preproprotein undergoes O- and N-glycosylation, and proteolytic processing to generate alpha and beta subunits. Certain mutations in this gene are known to cause distinct forms of muscular dystrophy. Alternative splicing results in multiple transcript variants, all encoding the same protein.
NCBI Gene ID
1605
Swiss Prot
Q14118
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 654-749 of human DAG1 (NP_004384.4) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
HepG2
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 43kDa/95kDa
Fragment
IgG
Symbol
DAG1
Positive Control 2
U2OS
Positive Control 3
SW480
Positive Control 4
HeLa
Positive Control 5
Mouse skeletal muscle
Positive Control 6
Mouse lung
NCBI Official Name
Dystroglycan 1 (dystrophin-associated glycoprotein 1)
NCBI Organism
Homo sapiens
Other Product Names
DAG1, dystroglycan 1 (dystrophin-associated glycoprotein 1), dystroglycan 1, DAG, beta-dystroglycan, alpha-dystroglycan, AGRNR, A3a, 156DAG, MDDGC7, MDDGC9
Tested Applications
WB, IF
Physical Properties
Liquid
Frequently Asked Questions
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