SCN1B Antibody
Product Specifications
Background
Voltage-gated sodium channels are heteromeric proteins that function in the generation and propagation of action potentials in muscle and neuronal cells. They are composed of one alpha and two beta subunits, where the alpha subunit provides channel activity and the beta-1 subunit modulates the kinetics of channel inactivation. This gene encodes a sodium channel beta-1 subunit. Mutations in this gene result in generalized epilepsy with febrile seizures plus, Brugada syndrome 5, and defects in cardiac conduction. Multiple transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
6324
Swiss Prot
Q07699
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 19-160 of human SCN1B (NP_950238.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
SH-SY5Y
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 30kDa
Fragment
IgG
Symbol
SCN1B
Positive Control 2
A-549
Positive Control 3
HeLa
Positive Control 4
MCF7
Positive Control 5
Mouse brain
Positive Control 6
Rat brain
NCBI Official Name
Sodium channel, voltage-gated, type I, beta subunit
NCBI Organism
Homo sapiens
Other Product Names
SCN1B, GEFSP1, ATFB13, BRGDA5
Tested Applications
WB, IHC
Physical Properties
Liquid
Curated Selection
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