CNTNAP1 Antibody
Product Specifications
Background
The gene product was initially identified as a 190-kD protein associated with the contactin-PTPRZ1 complex. The 1,384-amino acid protein, also designated p190 or CASPR for 'contactin-associated protein, ' includes an extracellular domain with several putative protein-protein interaction domains, a putative transmembrane domain, and a 74-amino acid cytoplasmic domain. Northern blot analysis showed that the gene is transcribed predominantly in brain as a transcript of 6.2 kb, with weak expression in several other tissues tested. The architecture of its extracellular domain is similar to that of neurexins, and this protein may be the signaling subunit of contactin, enabling recruitment and activation of intracellular signaling pathways in neurons.
NCBI Gene ID
8506
Swiss Prot
P78357
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 20-300 of human CNTNAP1 (NP_003623.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
Affinity purification
Positive Control
U-937
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=13-400
Calculated Molecular Weight
Observed: 170kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
CNTNAP1
Positive Control 2
PC-12
Positive Control 3
Mouse brain
Positive Control 4
Rat kidney
NCBI Official Name
Contactin associated protein 1
NCBI Organism
Homo sapiens
Other Product Names
CNTNAP1, CASPR, CNTNAP, NRXN4, P190
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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