EIG121 Antibody
Product Specifications
Background
EIG121 Antibody: EIG121 (Estrogen-induced gene 121 protein) is thought to play a role as a marker of hyperestrogenic state and estrogen-related type I endometrial carcinoma. It belongs to the UPF0577 family. It is a 1013 amino acid single-pass transmembrane protein that, though expressed in normal endometrium, is overexpressed in endometriod tumors. As an evolutionarily conserved gene, EIG121 is also expressed during early xenopus development, showing maximum expression at the gastrula stage.
NCBI Gene ID
57535
Swiss Prot
Q6UXG2
Accession Number
NP_065826
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Stem Cell
Purification
EIG121 Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1219 - MCF7 Cell Lysate
Concentration
1 mg/mL
Homology
Predicted species reactivity based on immunogen sequence: Mouse: (100%)
Buffer
EIG121 Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
EIG121 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgG
Specificity
At least four isoforms of EIG121 known to exist. EIG121 antibody is predicted to not cross-react with other UPF0577 protein family members.
Symbol
KIAA1324
Positive Control 2
Cat. No. 17-012 - MCF7 Cell Slide
NCBI Official Name
KIAA1324
NCBI Organism
Homo sapiens
Background Reference 01
Deng L, Broaddus RR, McCampbell A, et al. Identification of a novel estrogen-regulated gene, EIG121, induced by hormone replacement therapy and differentially expressed in type I and type II endometrial cancer. Clin. Cancer Res. 2005; 11:8258-64.
Background Reference 02
Deng L, Feng J, Broaddus RR. The novel estrogen-induced gene EIG121 regulates autophagy and promotes cell survival under stress. Cell Death Dis. 2010; 1:e32.
Background Reference 03
Araki T, Kusakabe M and Nishida E. Expression of estrogen induced gene 121-like (EIG121L) during early Xenopus development. Gene Expr. Patterns 2007; 7:666-71.
Other Product Names
EIG121 Antibody: EIG, EIG1
Tested Applications
ELISA, WB, ICC, IF
Protein ID
38569482
Physical Properties
Liquid
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
T2040-01-ML750 100 µL
TCR, alpha (T Cell Receptor) (MaxLight 750) discontinued
Sign In for Pricing
View Details 
