OKI-006
OKI-006 is a potent and orally active inhibitor of histone deacetylase (HDAC) . OKI-006 is a unique congener of the natural product HDAC inhibitor largazole. Histone deacetylases (HDACs) play critical roles in epigenomic regulation, and histone acetylation is dysregulated in many human cancers. OKI-006 has the potential for the research of cancer disease[1].
Product Specifications
CAS Number
[1315334-23-6]
UNSPSC
12352005
Target
HDAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/oki-006.html
Solubility
10 mM in DMSO
Smiles
SCC/C=C/[C@@H]1CC(NCC2=NC(C(NC(C)(C(N[C@H](C(O1)=O)C(C)C)=O)C)=O)=CS2)=O
Molecular Formula
C21H30N4O5S2
Molecular Weight
482.62
References & Citations
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-144893/OKI-006-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-144893/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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