Slc2a4 (NM_009204) Mouse Recombinant Protein
Product Specifications
Background
Insulin-regulated facilitative glucose transporter, which plays a key role in removal of glucose from circulation (PubMed:26240143, PubMed:26629404) . Response to insulin is regulated by its intracellular localization: in the absence of insulin, it is efficiently retained intracellularly within storage compartments in muscle and fat cells (PubMed:26240143, PubMed:26629404) . Upon insulin stimulation, translocates from these compartments to the cell surface where it transports glucose from the extracellular milieu into the cell (PubMed:26240143, PubMed:26629404) .[UniProtKB/Swiss-Prot Function]
Synonyms
Glut-4; Glut4; GT2; twgy
Gene ID
20528
UniProt
P14142
Accession Number mRNA
NM_009204
Chromosomal Location
11 42.93 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
55.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Slc2a4
Species
Mouse
Protein ID
NP_033230
Overview
Purified recombinant protein of Mouse solute carrier family 2 (facilitated glucose transporter), member 4 (Slc2a4), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/20528
Uniprot URL
https://www.uniprot.org/uniprot/P14142
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_009204
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_033230
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