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Slc2a4 (NM_009204) Mouse Recombinant Protein

Product Specifications

Background

Insulin-regulated facilitative glucose transporter, which plays a key role in removal of glucose from circulation (PubMed:26240143, PubMed:26629404) . Response to insulin is regulated by its intracellular localization: in the absence of insulin, it is efficiently retained intracellularly within storage compartments in muscle and fat cells (PubMed:26240143, PubMed:26629404) . Upon insulin stimulation, translocates from these compartments to the cell surface where it transports glucose from the extracellular milieu into the cell (PubMed:26240143, PubMed:26629404) .[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse solute carrier family 2 (facilitated glucose transporter), member 4 (Slc2a4), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

Glut-4; Glut4; GT2; twgy

Gene ID

20528

UniProt

P14142

Accession Number mRNA

NM_009204

Chromosomal Location

11 42.93 cM

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

55.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Slc2a4

Species

Mouse

Protein ID

NP_033230

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/20528

Uniprot URL

https://www.uniprot.org/uniprot/P14142

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_009204

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_033230

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