Mfn1 (NM_024200) Mouse Recombinant Protein
Product Specifications
Background
Mitochondrial outer membrane GTPase that mediates mitochondrial clustering and fusion (PubMed:12527753, PubMed:23921378, PubMed:24513856, PubMed:15297672) . Membrane clustering requires GTPase activity (By similarity) . It may involve a major rearrangement of the coiled coil domains (PubMed:15297672) . Mitochondria are highly dynamic organelles, and their morphology is determined by the equilibrium between mitochondrial fusion and fission events (PubMed:12527753) . Overexpression induces the formation of mitochondrial networks (in vitro) . Has low GTPase activity (By similarity) .[UniProtKB/Swiss-Prot Function]
Synonyms
2310002F04Rik; 6330416C07Rik; D3Ertd265e; HR2; mKIAA4032
Gene ID
67414
UniProt
Q811U4
Accession Number mRNA
NM_024200
Chromosomal Location
3 15.75 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
83.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Mfn1
Species
Mouse
Protein ID
NP_077162
Overview
Purified recombinant protein of Mouse mitofusin 1 (Mfn1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/67414
Uniprot URL
https://www.uniprot.org/uniprot/Q811U4
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_024200
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_077162
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