Ac-VAD-AFC
Product Specifications
UNSPSC Description
Ac-VAD-AFC is a fluorescent substrate for caspases and can be used to test the activity of caspases[1][2].
Target Antigen
Caspase
Type
Peptides
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ac-vad-afc.html
Solubility
10 mM in DMSO
Smiles
O=C1OC2=C(C=C1C(F)(F)F)C=CC(NC([C@@H](NC([C@@H](NC([C@@H](NC(C)=O)C(C)C)=O)C)=O)CC(O)=O)=O)=C2
Molecular Weight
556.49
References & Citations
[1]Choi WS, et al. Cleavage of Bax is mediated by caspase-dependent or -independent calpain activation in dopaminergic neuronal cells: protective role of Bcl-2. J Neurochem. 2001;77(6):1531-1541.|[2]Posadas I, et al. Acetaminophen induces human neuroblastoma cell death through NFKB activation. PLoS One. 2012;7(11):e50160.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P10276/Ac-VAD-AFC-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P10276/
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS7001732-01 0.05 mg
Rabbit anti-human Glutamate receptor ionotropic, NMDA 2A polyclonal Antibody
Ask
View Details 
MBS7001732-02 0.1 mg
Rabbit anti-human Glutamate receptor ionotropic, NMDA 2A polyclonal Antibody
Ask
View Details 
MBS7001732-03 5x 0.1 mg
Rabbit anti-human Glutamate receptor ionotropic, NMDA 2A polyclonal Antibody
Ask
View Details