REC8 (NM_005132) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the kleisin family of SMC (structural maintenance of chromosome) protein partners. The protein localizes to the axial elements of chromosomes during meiosis in both oocytes and spermatocytes. In the mouse, the homologous protein is a key component of the meiotic cohesion complex, which regulates sister chromatid cohesion and recombination between homologous chromosomes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms
HR21spB; REC8L1; Rec8p
Gene ID
9985
UniProt
O95072
Accession Number mRNA
NM_005132
Chromosomal Location
14q12
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Oocyte meiosis
Field of Research
Oocyte meiosis
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
62.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
REC8
Species
Human
Protein ID
NP_005123
Overview
Recombinant protein of human REC8 homolog (yeast) (REC8), transcript variant 1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/9985
Uniprot URL
https://www.uniprot.org/uniprot/O95072
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_005132
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_005123
Curated Selection
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