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REC8 (NM_005132) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of the kleisin family of SMC (structural maintenance of chromosome) protein partners. The protein localizes to the axial elements of chromosomes during meiosis in both oocytes and spermatocytes. In the mouse, the homologous protein is a key component of the meiotic cohesion complex, which regulates sister chromatid cohesion and recombination between homologous chromosomes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human REC8 homolog (yeast) (REC8), transcript variant 1

Synonyms

HR21spB; REC8L1; Rec8p

Gene ID

9985

UniProt

O95072

Accession Number mRNA

NM_005132

Chromosomal Location

14q12

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Oocyte meiosis

Field of Research

Oocyte meiosis

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

62.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

REC8

Species

Human

Protein ID

NP_005123

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/9985

Uniprot URL

https://www.uniprot.org/uniprot/O95072

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_005132

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_005123

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