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Carbonic Anhydrase III (CA3) (NM_005181) Human Recombinant Protein

Product Specifications

Background

Carbonic anhydrase III (CAIII) is a member of a multigene family (at least six separate genes are known) that encodes carbonic anhydrase isozymes. These carbonic anhydrases are a class of metalloenzymes that catalyze the reversible hydration of carbon dioxide and are differentially expressed in a number of cell types. The expression of the CA3 gene is strictly tissue specific and present at high levels in skeletal muscle and much lower levels in cardiac and smooth muscle. A proportion of carriers of Duchenne muscle dystrophy have a higher CA3 level than normal. The gene spans 10.3 kb and contains seven exons and six introns. [provided by RefSeq, Oct 2008]

Synonyms

CAIII; Car3

Gene ID

761

UniProt

P07451, V9HWA3

Accession Number mRNA

NM_005181

Chromosomal Location

8q21.2

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Nitrogen metabolism

Field of Research

Nitrogen metabolism

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

29.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

CA3

Species

Human

Protein ID

NP_005172

Overview

Recombinant protein of human carbonic anhydrase III, muscle specific (CA3)

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/761

Uniprot URL

https://www.uniprot.org/uniprot/P07451

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_005181

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_005172

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