Carbonic Anhydrase III (CA3) (NM_005181) Human Recombinant Protein
Product Specifications
Background
Carbonic anhydrase III (CAIII) is a member of a multigene family (at least six separate genes are known) that encodes carbonic anhydrase isozymes. These carbonic anhydrases are a class of metalloenzymes that catalyze the reversible hydration of carbon dioxide and are differentially expressed in a number of cell types. The expression of the CA3 gene is strictly tissue specific and present at high levels in skeletal muscle and much lower levels in cardiac and smooth muscle. A proportion of carriers of Duchenne muscle dystrophy have a higher CA3 level than normal. The gene spans 10.3 kb and contains seven exons and six introns. [provided by RefSeq, Oct 2008]
Synonyms
CAIII; Car3
Gene ID
761
UniProt
P07451, V9HWA3
Accession Number mRNA
NM_005181
Chromosomal Location
8q21.2
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Nitrogen metabolism
Field of Research
Nitrogen metabolism
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
29.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
CA3
Species
Human
Protein ID
NP_005172
Overview
Recombinant protein of human carbonic anhydrase III, muscle specific (CA3)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/761
Uniprot URL
https://www.uniprot.org/uniprot/P07451
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_005181
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_005172
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items