HSD17B13-IN-66

Product Specifications

CAS Number

2770247-37-3

Target

Dehydrogenase

Related Pathways

Metabolism

Bioactivity

HSD17B13-IN-66 (Compound 146), an inhibitor of hydroxysteroid 17?-dehydrogenase 13 (HSD17B13), shows a potent IC 50 value of ? 0.1 ?M for estradiol. This compound is primarily utilized in research pertaining to liver diseases, metabolic disorders, and cardiovascular conditions, including non-alcoholic fatty liver disease (NAFLD), non-alcoholic steatohepatitis (NASH), and drug-induced liver injury (DILI) [1].

Smiles

N(C(=O)C1=CC(Cl)=C(O)C(Cl)=C1)C2=C3C(N=C(C)N(CC4=C(C(F)(F)F)C=CC=N4)C3=O)=C(C)C=C2

Molecular Formula

C24H17Cl2F3N4O3

Molecular Weight

537.32

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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