KIF20A (NM_005733) Human Recombinant Protein
Product Specifications
Background
Mitotic kinesin required for chromosome passenger complex (CPC) -mediated cytokinesis. Following phosphorylation by PLK1, involved in recruitment of PLK1 to the central spindle. Interacts with guanosine triphosphate (GTP) -bound forms of RAB6A and RAB6B. May act as a motor required for the retrograde RAB6 regulated transport of Golgi membranes and associated vesicles along microtubules. Has a microtubule plus end-directed motility.[UniProtKB/Swiss-Prot Function]
Overview
Recombinant protein of human kinesin family member 20A (KIF20A)
Synonyms
MKLP2; RAB6KIFL
Gene ID
10112
UniProt
O95235
Accession Number mRNA
NM_005733
Chromosomal Location
5q31.2
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
100.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
KIF20A
Species
Human
Protein ID
NP_005724
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/10112
Uniprot URL
https://www.uniprot.org/uniprot/O95235
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_005733
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_005724
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