Josephin 1 (JOSD1) (NM_014876) Human Recombinant Protein
Product Specifications
Background
Deubiquitinates monoubiquitinated probes (in vitro) . When ubiquitinated, cleaves 'Lys-63'-linked and 'Lys-48'-linked poly-ubiquitin chains (in vitro), hence may act as a deubiquitinating enzyme. May increase macropinocytosis and suppress clathrin- and caveolae-mediated endocytosis. May enhance membrane dynamics and cell motility independently of its catalytic activity.[UniProtKB/Swiss-Prot Function]
Synonyms
DJ508I15.2
Gene ID
9929
UniProt
Q15040, A0A024R1P5
Accession Number mRNA
NM_014876
Chromosomal Location
22q13.1
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
23 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
JOSD1
Species
Human
Protein ID
NP_055691
Overview
Recombinant protein of human Josephin domain containing 1 (JOSD1)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/9929
Uniprot URL
https://www.uniprot.org/uniprot/Q15040
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_014876
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_055691
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