GALT (NM_000155) Human Recombinant Protein

Product Specifications

Background

Galactose-1-phosphate uridyl transferase (GALT) catalyzes the second step of the Leloir pathway of galactose metabolism, namely the conversion of UDP-glucose + galactose-1-phosphate to glucose-1-phosphate + UDP-galactose. The absence of this enzyme results in classic galactosemia in humans and can be fatal in the newborn period if lactose is not removed from the diet. The pathophysiology of galactosemia has not been clearly defined. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]

Overview

Recombinant protein of human galactose-1-phosphate uridylyltransferase (GALT)

Synonyms

Galactose-1-phosphate uridyl transferase; galactose-1-phosphate uridylyltransferase; OTTHUMP00000021298

Gene ID

2592

UniProt

P07902, A0A0S2Z3Y7, B2RAT6

Accession Number mRNA

NM_000155

Chromosomal Location

9p13.3

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Amino sugar and nucleotide sugar metabolism, Galactose metabolism, Metabolic pathways

Field of Research

Amino sugar and nucleotide sugar metabolism, Galactose metabolism, Metabolic pathways

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

43.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.