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ING4 (NM_016162) Human Recombinant Protein

Product Specifications

Background

This gene encodes a tumor suppressor protein that contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in the TP53-dependent regulatory pathway. Multiple alternatively spliced transcript variants have been observed that encode distinct proteins. [provided by RefSeq, Jul 2008]

Synonyms

My036; p29ING4

Gene ID

51147

UniProt

Q9UNL4

Accession Number mRNA

NM_016162

Chromosomal Location

12p13.31

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Transcription Factors

Molecular Weight

28.3 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

ING4

Species

Human

Protein ID

NP_057246

Overview

Recombinant protein of human inhibitor of growth family, member 4 (ING4), transcript variant 1

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/51147

Uniprot URL

https://www.uniprot.org/uniprot/Q9UNL4

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_016162

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_057246

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