DNA Polymerase lambda (POLL) (NM_013274) Human Recombinant Protein

Product Specifications

Background

This gene encodes a DNA polymerase. DNA polymerases catalyze DNA-template-directed extension of the 3'-end of a DNA strand. This particular polymerase, which is a member of the X family of DNA polymerases, likely plays a role in non-homologous end joining and other DNA repair processes. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2010]

Overview

Recombinant protein of human polymerase (DNA directed), lambda (POLL)

Synonyms

BETAN; POLKAPPA

Gene ID

27343

UniProt

Q9UGP5

Accession Number mRNA

NM_013274

Chromosomal Location

10q24.32

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Base excision repair, Non-homologous end-joining

Field of Research

Base excision repair, Non-homologous end-joining

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

63.3 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.