L-796778

L-796778 is a selective agonist of the sst3 receptor. In CHO-K1 cells expressing the hsst3 receptor, L-796778 is a partial agonist that inhibits Forskolin (HY-15371) -stimulated cAMP production with an IC50 value of 18 nM. L-796778 has anticonvulsant effect[1].

Product Specifications

CAS Number

[217480-25-6]

UNSPSC

12352005

Target

Somatostatin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/l-796-778.html

Purity

98.00

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C([C@H](CCCCN)NC([C@@H](CCCC)NC(N[C@H](C(NC1=CC=C(C=C1)[N+]([O-])=O)=O)CC2=CC=CC=C2)=O)=O)OC

Molecular Formula

C29H40N6O7

Molecular Weight

584.66

References & Citations

[1]Pfeiffer M, et al. Homo- and heterodimerization of somatostatin receptor subtypes. Inactivation of sst (3) receptor function by heterodimerization with sst (2A) . J Biol Chem. 2001 Apr 27;276 (17) :14027-36.