ALKBH3 (NM_139178) Human Recombinant Protein
Product Specifications
Background
The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 (MIM 610602) and ALKBH3 are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine (Duncan et al., 2002 [PubMed 12486230]) .[supplied by OMIM, Mar 2008]
Overview
Recombinant protein of human alkB, alkylation repair homolog 3 (E. coli) (ALKBH3)
Synonyms
ABH3; DEPC-1; DEPC1; hABH3; PCA1
Gene ID
221120
UniProt
Q96Q83
Accession Number mRNA
NM_139178
Chromosomal Location
11p11.2
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
33.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
ALKBH3
Species
Human
Protein ID
NP_631917
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/221120
Uniprot URL
https://www.uniprot.org/uniprot/Q96Q83
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_139178
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_631917
Curated Selection
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