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PRMT1 (NM_198319) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of the protein arginine N-methyltransferase (PRMT) family. Post-translational modification of target proteins by PRMTs plays an important regulatory role in many biological processes, whereby PRMTs methylate arginine residues by transferring methyl groups from S-adenosyl-L-methionine to terminal guanidino nitrogen atoms. The encoded protein is a type I PRMT and is responsible for the majority of cellular arginine methylation activity. Increased expression of this gene may play a role in many types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Dec 2011]

Overview

Recombinant protein of human protein arginine methyltransferase 1 (PRMT1), transcript variant 2

Synonyms

6720434D09Rik; ANM1; arginine N-methyltransferase 1; AW214366; HCP1; heterogeneous nuclear ribonucleoproteins methyltransferase-like 2; HRMT1L2; Hrmt1l2; IR1B4; Mrmt1; OTTMUSP00000022387; protein arginine N-methyltransferase 1

Gene ID

3276

UniProt

Q99873

Accession Number mRNA

NM_198319

Chromosomal Location

19q13.33

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

42.3 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

PRMT1

Species

Human

Protein ID

NP_938075

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/3276

Uniprot URL

https://www.uniprot.org/uniprot/Q99873

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_198319

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_938075

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