PROP1 (NM_006261) Human Recombinant Protein
Product Specifications
Background
This gene encodes a paired-like homeodomain transcription factor in the developing pituitary gland. Expression occurs prior to and is required for expression of pou domain transcription factor 1, which is responsible for pituitary development and hormone expression. Mutations in this gene have been associated with combined pituitary hormone deficiency-2 as well as deficiencies in luteinizing hormone, follicle-stimulating hormone, growth hormone, prolactin, and thyroid-stimulating hormone. [provided by RefSeq, Sep 2011]
Synonyms
CPHD2; PROP-1
Gene ID
5626
UniProt
O75360, A0A0G2JQ02
Accession Number mRNA
NM_006261
Chromosomal Location
5q35.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Transcription Factors
Molecular Weight
24.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
PROP1
Species
Human
Protein ID
NP_006252
Overview
Recombinant protein of human PROP paired-like homeobox 1 (PROP1)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/5626
Uniprot URL
https://www.uniprot.org/uniprot/O75360
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_006261
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_006252
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