ECE1 (NM_001397) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is involved in proteolytic processing of endothelin precursors to biologically active peptides. Mutations in this gene are associated with Hirschsprung disease, cardiac defects and autonomic dysfunction. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Sep 2009]
Overview
Purified recombinant protein of Homo sapiens endothelin converting enzyme 1 (ECE1), transcript variant 1
Synonyms
ECE
Gene ID
1889
UniProt
P42892, A1PUP8
Accession Number mRNA
NM_001397
Chromosomal Location
1p36.12
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Protease, Transmembrane
Molecular Weight
87 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
ECE1
Species
Human
Protein ID
NP_001388
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/1889
Uniprot URL
https://www.uniprot.org/uniprot/P42892
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001397
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001388
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