PER1 Polyclonal Antibody
Product Specifications
Background
This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene may increase the risk of getting certain cancers. Alternative splicing has been observed in this gene; however, these variants have not been fully described.
Abbreviation
PER1
UniProt
O15534
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant fusion protein of human PER1 (NP_002607.2) .
Target
PER1; PER; RIGUI; hPER
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC; IF
Field of Research
Epigenetics and Nuclear Signaling; Neuroscience
Purification
Affinity purification
Concentration
1mg/mL
Dilution
IHC 1:50-1:100; IF 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG
Available Sizes
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