RGS3 (NM_021106) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the regulator of G-protein signaling (RGS) family. This protein is a GTPase-activating protein that inhibits G-protein-mediated signal transduction. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different isoforms. Long isoforms are largely cytosolic and plasma membrane-associated with a function in Wnt signaling and in the epithelial mesenchymal transition, while shorter N-terminally-truncated isoforms can be nuclear. [provided by RefSeq, Jan 2013]
Overview
Recombinant protein of human regulator of G-protein signaling 3 (RGS3), transcript variant 2
Synonyms
C2PA; PDZ-RGS3; RGP3
Gene ID
5998
UniProt
P49796
Accession Number mRNA
NM_021106
Chromosomal Location
9q32
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Axon guidance
Field of Research
Axon guidance
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
56.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
RGS3
Species
Human
Protein ID
NP_066929
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/5998
Uniprot URL
https://www.uniprot.org/uniprot/P49796
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_021106
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_066929
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