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KGF (FGF7) (NM_002009) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. Studies of mouse and rat homologs of this gene implicated roles in morphogenesis of epithelium, reepithelialization of wounds, hair development and early lung organogenesis. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human fibroblast growth factor 7 (keratinocyte growth factor) (FGF7)

Synonyms

HBGF-7; KGF

Gene ID

2252

UniProt

P21781

Accession Number mRNA

NM_002009

Chromosomal Location

15q21.2

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

MAPK signaling pathway, Melanoma, Pathways in cancer, Regulation of actin cytoskeleton

Field of Research

MAPK signaling pathway, Melanoma, Pathways in cancer, Regulation of actin cytoskeleton

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Adult stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Secreted Protein

Molecular Weight

18.8 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

FGF7

Species

Human

Protein ID

NP_002000

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/2252

Uniprot URL

https://www.uniprot.org/uniprot/P21781

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_002009

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_002000

Frequently Asked Questions

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