TMEM30B (NM_001017970) Human Recombinant Protein
Product Specifications
Background
Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. The beta subunit may assist in binding of the phospholipid substrate (Probable) . Can mediate the export of alpha subunits ATP8A1, ATP8B1, ATP8B2 and ATP8B4 from the ER to the plasma membrane.[UniProtKB/Swiss-Prot Function]
Synonyms
CDC50B
Gene ID
161291
UniProt
Q3MIR4
Accession Number mRNA
NM_001017970
Chromosomal Location
14q23.1
Expression System
E. coli
Tag
N-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
50mM Tris, 8M Urea, pH8.0.
Function
Transmembrane
Molecular Weight
25.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
TMEM30B
Species
Human
Protein ID
NP_001017970
Overview
Purified recombinant protein of Human transmembrane protein 30B (TMEM30B), Ser57-Arg284, with N-terminal His tag, expressed in E.coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/161291
Uniprot URL
https://www.uniprot.org/uniprot/Q3MIR4
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001017970
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001017970
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