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TMEM30B (NM_001017970) Human Recombinant Protein

Product Specifications

Background

Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. The beta subunit may assist in binding of the phospholipid substrate (Probable) . Can mediate the export of alpha subunits ATP8A1, ATP8B1, ATP8B2 and ATP8B4 from the ER to the plasma membrane.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Human transmembrane protein 30B (TMEM30B), Ser57-Arg284, with N-terminal His tag, expressed in E.coli, 50ug

Synonyms

CDC50B

Gene ID

161291

UniProt

Q3MIR4

Accession Number mRNA

NM_001017970

Chromosomal Location

14q23.1

Expression System

E. coli

Tag

N-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

50mM Tris, 8M Urea, pH8.0.

Function

Transmembrane

Molecular Weight

25.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

TMEM30B

Species

Human

Protein ID

NP_001017970

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/161291

Uniprot URL

https://www.uniprot.org/uniprot/Q3MIR4

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_001017970

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001017970

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