VUF11211
VUF11211 is an allosteric inverse CXCR3 agonist with a Kd of 0.65 nM[1].
Product Specifications
CAS Number
[906556-51-2]
UNSPSC
12352005
Target
CXCR
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/vuf11211.html
Solubility
10 mM in DMSO
Smiles
ClC1=CC=C(C=C1)CN2CCC(CC2)N3[C@H](CN(CC3)C4=NC=C(C=C4Cl)C(NCC)=O)CC
Molecular Formula
C26H35Cl2N5O
Molecular Weight
504.50
References & Citations
[1]Scholten DJ, et al. Pharmacological characterization of [3H]VUF11211, a novel radiolabeled small-molecule inverse agonist for the chemokine receptor CXCR3. Mol Pharmacol. 2015 Apr;87 (4) :639-48.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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