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GATA3 (NM_001002295) Human Recombinant Protein

Product Specifications

Background

This gene encodes a protein which belongs to the GATA family of transcription factors. The protein contains two GATA-type zinc fingers and is an important regulator of T-cell development and plays an important role in endothelial cell biology. Defects in this gene are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia. [provided by RefSeq, Nov 2009]

Overview

Purified recombinant protein of Human GATA binding protein 3 (GATA3), transcript variant 1, Pro189-Ser201 (8 reapeat regions linked with GGGGS), with N-terminal His tag, expressed in E.coli, 50ug

Synonyms

HDR; HDRS

Gene ID

2625

UniProt

P23771

Accession Number mRNA

NM_001002295

Chromosomal Location

10p14

Expression System

E. coli

Tag

N-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150mM NaCl, 10% glycerol

Function

Adult stem cells, ES Cell Differentiation/IPS, Stem cell relevant signaling - JAK/STAT signaling pathway, Transcription Factors

Molecular Weight

13.5 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

GATA3

Species

Human

Protein ID

NP_001002295

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/2625

Uniprot URL

https://www.uniprot.org/uniprot/P23771

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_001002295

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001002295

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