Anp32e (NM_023210) Mouse Recombinant Protein
Product Specifications
Background
Histone chaperone that specifically mediates the genome-wide removal of histone H2A.Z/H2AFZ from the nucleosome: removes H2A.Z/H2AFZ from its normal sites of deposition, especially from enhancer and insulator regions. Not involved in deposition of H2A.Z/H2AFZ in the nucleosome. May stabilize the evicted H2A.Z/H2AFZ-H2B dimer, thus shifting the equilibrium towards dissociation and the off-chromatin state (PubMed:24463511) . Inhibits activity of protein phosphatase 2A (PP2A) . Does not inhibit protein phosphatase 1. May play a role in cerebellar development and synaptogenesis.[UniProtKB/Swiss-Prot Function]
Synonyms
2810018A15Rik; AI047746; AI326868; CPD1; LANP-L; LANPL; mLANP-L
Gene ID
66471
UniProt
P97822
Accession Number mRNA
NM_023210
Chromosomal Location
3 F2.1
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
30.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Anp32e
Species
Mouse
Protein ID
NP_075699
Overview
Purified recombinant protein of Mouse acidic (leucine-rich) nuclear phosphoprotein 32 family, member E (Anp32e), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/66471
Uniprot URL
https://www.uniprot.org/uniprot/P97822
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_023210
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_075699
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