Atg5 (NM_053069) Mouse Recombinant Protein
Product Specifications
Background
The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regulation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. Two transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Sep 2015]
Synonyms
2010107M05Rik; 3110067M24Rik; Ap; Apg5l; Atg5l; AW319544; C88337; Pad; Paddy
Gene ID
11793
UniProt
Q99J83
Accession Number mRNA
NM_053069
Chromosomal Location
10 23.24 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
32.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Atg5
Species
Mouse
Protein ID
NP_444299
Overview
Purified recombinant protein of Mouse autophagy related 5 (Atg5), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/11793
Uniprot URL
https://www.uniprot.org/uniprot/Q99J83
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_053069
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_444299
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