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KMT1B/SUV39H2 Rabbit Monoclonal Antibody

Product Specifications

Background

Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 using monomethylated H3 'Lys-9' as substrate. H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Mainly functions in heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin at pericentric and telomere regions.

Product Name Alternative

H3 K9 HMTase 2; KMT1B; Su (var) 3 9 homolog 2; Suv39h2; ; KMT1B

Gene Name

KMT1B/SUV39H2

Swiss Prot

Q9H5I1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, IHC, IP

Purification

Affinity Purification

Dilution

WB 1:1000-1:2000, IHC 1:100-1:200, IP 1:20-1:50

Form

Liquid

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

Modification

Unmodified

Molecular Weight

47 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

Curated Selection

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