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Nfe2 (NM_008685) Mouse Recombinant Protein

Selected Variant

PM46854M5

Size: 20 µg

Product Specifications

Background

Component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. Binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR) . This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. Requires MAFK or other small MAF proteins for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse nuclear factor, erythroid derived 2 (Nfe2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

NF-E2; NF-E2/P45; p45; p45nf-e2; p45NFE2

Gene ID

18022

UniProt

Q07279, A0A0R4J0Y5

Accession Number mRNA

NM_008685

Chromosomal Location

15 58.62 cM

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

42 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Nfe2

Species

Mouse

Protein ID

NP_032711

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/18022

Uniprot URL

https://www.uniprot.org/uniprot/Q07279

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_008685

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_032711

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