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Psmd11 (NM_178616) Mouse Recombinant Protein

Product Specifications

Background

Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. In the complex, PSMD11 is required for proteasome assembly. Plays a key role in increased proteasome activity in embryonic stem cells (ESCs) : its high expression in ESCs promotes enhanced assembly of the 26S proteasome, followed by higher proteasome activity.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 (Psmd11), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

1700089D09Rik; 1810019E17Rik; 2610024G20Rik; 2810055C24Rik; C78232; P44.5; S9

Gene ID

69077

UniProt

Q8BG32, Q5BKQ9, Q3UWW9

Accession Number mRNA

NM_178616

Chromosomal Location

11 B5

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

47.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Psmd11

Species

Mouse

Protein ID

NP_848731

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/69077

Uniprot URL

https://www.uniprot.org/uniprot/Q8BG32

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_178616

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_848731

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