Nsun2 (BC013625) Mouse Recombinant Protein
Product Specifications
Background
RNA methyltransferase that methylates tRNAs, and possibly RNA polymerase III transcripts. Methylates cytosine to 5-methylcytosine (m5C) at positions 34 and 48 of intron-containing tRNA (Leu) (CAA) precursors, and at positions 48, 49 and 50 of tRNA (Gly) (GCC) precursors (By similarity) . May act downstream of Myc to regulate epidermal cell growth and proliferation. Required for proper spindle assembly and chromosome segregation, independently of its methyltransferase activity.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse NOL1/NOP2/Sun domain family 2 (cDNA clone MGC:18985 IMAGE:4011674), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
D13Wsu123e; Misu
Gene ID
28114
UniProt
Q1HFZ0
Accession Number mRNA
BC013625
Chromosomal Location
13 35.55 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
58.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Nsun2
Species
Mouse
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/28114
Uniprot URL
https://www.uniprot.org/uniprot/Q1HFZ0
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/BC013625
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